Author

Tian-Yu Zhang

2 papers indexed here

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Open access Sep 2026

Colquhounia Root Tablet Modulates Psoriatic Immune Responses Involving NF-κB-Driven Dendritic-Cell Maturation and Th17/Treg Imbalance: An Integrative Network Pharmacology and Transcriptomic Study

Background/Objectives: Psoriasis is a chronic inflammatory skin disease driven by Th17/Treg imbalance. Colquhounia Root Tablet (CRT), derived from Tripterygium hypoglaucum, has shown clinical potential for psoriasis, but its mechanisms remain unclear. This study aimed to evaluate the anti-psoriatic effects of CRT and e...

Qing-Qing Xu, Li-Song Sheng, Hui Zhao et al. · Pharmaceutics · 0 citations

Open access Jan 2026

Diosmetin Restores Endoplasmic Reticulum Homeostasis to Ameliorate Podocyte Injury in Diabetic Kidney Disease by Targeting DNAJC3

This study clarifies the molecular basis of DIO‐mediated protection in DKD, particularly in podocytes, by identifying DNAJC3 as a potential target that DIO inhibits ERS, restores ER homeostasis, and alleviates podocyte injury.

Tian-Yu Zhang, Na Zhao, Tong-Jin Liu et al. · Journal of Diabetes Research · 0 citations