Sep 2026
Direct Cytosolic Protein Delivery via Near-Infrared-Driven Membrane-Intercalating Conjugated Oligoelectrolytes
The intracellular delivery of functional proteins remains a major challenge due to the impermeability of the plasma membrane and inefficient endosomal escape. Here, we report a membrane-intercalating conjugated oligoelectrolyte (MI-COE, BBTN) that enables near-infrared (NIR)-triggered direct cytosolic protein deliver...
Xue Zhai, Fan Xu, Peng Su et al.
· Chemistry of Materials · 0 citations