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Tianyuan Lu

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Open access Sep 2026

Integrative plasma proteomic network analysis identifies physical activity-associated protein modules potentially mediating type 2 diabetes risk

Moderate-to-vigorous physical activity (MVPA) lowers the risk of type 2 diabetes (T2D). Identifying protein modules that mediate this association may help dissect these biological underpinnings, but they remain incompletely characterized. We studied 28,842 diabetes-free UK Biobank participants with baseline plasma prot...

Zhen-Qian Wang, Chen-Yang Su, Jia-Wen Lu et al. · 0 citations
Sep 2026

Multi-omics integration of transcriptomics and metabolomics with machine learning uncovers novel risk factors for Alzheimer's disease.

BackgroundAlzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, memory impairment, and functional deterioration. Its complex pathogenesis involves amyloid plaques, tau tangles, neuroinflammation, synaptic dysfunction, and interacting genetic, environmental, and lifestyle factors....

Jerome J. Choi, C. Engelman, Tianyuan Lu · 0 citations

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