Aug 2026
Parishin degrades CXCL2 via ubiquitination to limit myeloid-derived suppressor cells and potentiate antitumor immunity after incomplete radiofrequency ablation in hepatocellular carcinoma.
This study elucidates the adverse role of the CXCL2/MDSC axis in the prognosis of post-iRFA HCC and reveals a novel "Parishin-CXCL2 ubiquitination" mechanism.
Wenbo Wang, Yuhan Shen, Jian Yuan et al.
· International Immunopharmaco... · 0 citations