Jul 2026
Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance.
This work pioneers the development of CA-targeted degraders, providing a framework for next-generation anti-HIV therapies with high potency and resistance barriers, via a proteasome-driven pathway.
Mei Wang, Ze-Yu Peng, Yang Zhou et al.
· Journal of Medicinal Chemist... · 0 citations