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Author

Tien-Dung Bui

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Review Oct 2026

Cell-free DNA fragmentomics: from chromatin biology to clinical stratification.

Plasma cell-free DNA (cfDNA) is fragmented nonrandomly, reflecting the chromatin architecture of its source cells and the nucleases that process it. The fragmentome can therefore provide an indirect readout of cellular regulatory state. This review examines how DNA methylation, chromatin accessibility, nucleosome posit...

Tien-Dung Bui, M. Phùng, Teh-Ying Chou et al. · 0 citations

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