Differential effects of psilocybin derivatives on fentanyl-induced conditioned place preference in male and female mice.
BACKGROUND Fentanyl is the leading cause of fatal overdoses worldwide, and repeated use may lead to substance use disorder (SUD). In SUD, drug-associated contexts can trigger reward-related behavior even in the absence of the drug. Psychedelic compounds may weaken context-drug associations, reducing reward-related beha...