Timosh Rueff

Thrombopoietin signaling and a dedicated cytoskeleton regulate murine hematopoietic stem cell motility

During development, transplantation, and homeostasis, hematopoietic stem cells (HSCs) migrate to niches to (re)constitute and maintain the hematopoietic system. A solid mechanistic understanding of their movement is essential but remains poorly examined. Here, we used long-term single-cell imaging and tracking to qua...