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Author

Timothy Pham

2 papers indexed here

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Open access Sep 2026

Real-world estrogen receptor alpha 1 (ESR1) testing patterns and results for ER+/HER2- metastatic breast cancer in the United States, 2018–2024

To understand historical and recent ESR1 testing rates, and when ESR1 mutations emerge during first-line (1 L) treatment. This retrospective, observational cohort study used the Flatiron Health Research Database (FHRD) and the Flatiron Health-Foundation Medicine metastatic breast cancer (mBC) Clinico-Genomic Database (...

J. Meisel, Timothy Pham, Clara Chen et al. · 0 citations
Open access Sep 2026

Real-world treatment patterns and clinical outcomes in patients with emerging estrogen receptor 1 (ESR1)-mutated ER+ metastatic breast cancer in the U.S., 2018-2024

The findings highlight the clinical relevance of ESR1m emergence prior to progression and underscore the need for strategies to better identify and manage patients with emerging endocrine resistance.

J. Meisel, Clara Chen, A. Kris et al. · 0 citations

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