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Open access Sep 2026

SOX2 Inhibits Cuproptosis to Affect Cisplatin Resistance in Non‐Small Cell Lung Cancer by Activating the Wnt/ATP7B Signaling Pathway

ABSTRACT Cisplatin (CDDP) resistance constitutes the principal clinical challenge in the treatment of advanced non‐small cell lung cancers (NSCLC). Disturbances in copper metabolism are closely linked with tumor drug resistance. SOX2, a pivotal stemness transcription factor (TF), holds an important role in chemotherapy...

Kun Chen, Fu-Mei He, Ying-Hui Huang et al. · 0 citations

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