Open access
Aug 2026
Hippo Pathway Regulation and Microenvironmental Cues Governing Human MSC Transition to Cancer‐Associated Fibroblasts
Cancer‐associated fibroblasts (CAFs) are key drivers of tumor progression. This study examined how three‐dimensional (3D) culture, hypoxia, and cancer‐derived soluble factors influence the transformation of human mesenchymal stem cells (hMSCs) into inflammatory CAFs (iCAFs). hMSCs from bone marrow, placenta, and chorio...
Pimjai Chingsuwanrote, C. Lorthongpanich, P. Kheolamai et al.
· Journal of Cellular Physiolo... · 0 citations