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Ting-Ting Lv

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Open access Sep 2026

Tumor-cell HMGB1 restrains CD8+ T-cell immunity during conventional fractionated radiotherapy.

Conventional fractionated radiotherapy (CFRT) remains a mainstay for many solid tumors, yet it often fails to elicit durable anti-tumor immunity. How CFRT engages tumor-cell programs to shape the immune microenvironment and determine therapeutic outcome remains unclear. Here we show in preclinical mouse models that CFR...

Chen Chen, Jia-Hong Shi, P. Cao et al. · 0 citations

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