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Author

Ting-Xiu Xiang

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Open access Oct 2026

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer‐related mortality. Integrative multi‐omics and machine‐learning analyses across independent cohorts identified CYYR1 as a frequently downregulated transmembrane protein in LUAD, with low expression associated with poor prognosis and promoter hypermet...

Feng-Sheng Dai, Jing-Yi Tang, Huan Rong et al. · 0 citations
Open access Oct 2026

Aberrant CPS1 expression is linked to metabolic alterations and metastatic phenotypes in colorectal cancer liver metastasis

Colorectal carcinoma liver metastasis (CRLM) is the main cause of mortality in colorectal cancer (CRC), yet its metabolic drivers remain poorly understood. Here, we integrated three GEO datasets to identify metabolic reprogramming signatures distinguishing CRLM compared to primary tumors. A four-gene metabolism-relat...

Qin Xiang, Ming Yang, Xiao-Yue Li et al. · 0 citations

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