Discovering repurposable drugs for Alzheimer’s disease and related dementias: target trial emulation using decentralised real-world data
Summary Background Alzheimer’s disease and related dementias (ADRD) affect nearly 6.9 million Americans, with the number expected to triple by 2050, while disease-modifying therapies remain unavailable. Drug repurposing, which identifies new indications for already approved medications, offers a more efficient and cost...