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Author

To-Ni Q. Duan

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Review Open access Aug 2026

Iron regulation by Sirtuins 1 & 2 and their therapeutic modulation by Sirtinol

This review focuses on the role of SIRTs 1 & 2 as tumor promoters, providing a rationale for developing inhibitors like sirtinol for these enzymes, and examines sirtinol’s anti-tumor properties in relation to its ability to function as a tridentate iron chelator.

Koffi Amegble, Lu-Jia Liu, To-Ni Q. Duan et al. · 0 citations

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