Author

Tobias Wertheimer

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Open access Sep 2026

Characterisation of TP53 mutational features and outcomes of acute myeloid leukaemia after allogeneic haematopoietic cell transplantation.

TP53 mutations define a clinically distinct subset of acute myeloid leukaemia (AML) associated with complex cytogenetics and therapy resistance. We performed a retrospective single-centre analysis of 61 consecutive TP53-altered AML patients undergoing first allogeneic haematopoietic cell transplantation (allo-HCT) at t...

M. Reuss, Thomas Meyer, Florian Ingelfinger et al. · Bone Marrow Transplantation · 0 citations

Open access Sep 2026

CytoVI: deep generative modeling of antibody-based single cell data.

Antibody-based single-cell technologies, such as flow cytometry, mass cytometry and CITE-seq, have become widely used in clinical diagnostics and basic research; however, their analysis is complicated by technical noise, batch effects, platform differences and restricted antibody panels. Here we present CytoVI, a proba...

Florian Ingelfinger, Nathan Levy, Can Ergen et al. · Nature Methods · 0 citations