Tom S. Weber

Upregulation of CD90 correlates with T lineage commitment at the DN2a stage of T cell development

Early thymic progenitors (ETPs) retain the potential for alternative fates but commit to the T-cell lineage as they progress through the CD4−CD8− double-negative (DN) thymocyte stages early in T-cell development. Current evidence suggests that T-lineage commitment occurs during the transition from the DN2a to DN2b stag...