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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Tomáš Čajka

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2 papers indexed here

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Open access Aug 2026

Using Hydrogen/Deuterium Exchange in Untargeted LC-MS Analysis of Small Molecules

Liquid chromatography–hydrogen/deuterium exchange–mass spectrometry (LC-HDX-MS) provides orthogonal structural information that complements conventional LC-MS and improves confidence in small-molecule structural elucidation. Although HDX-MS is well established in protein research, its application to small molecules rem...

Tomáš Čajka, J. Hricko, Lucie Rudl Kulhavá et al. · 0 citations
Open access Aug 2026

Polyunsaturated fatty acid sequestration protects against mitochondrial dysfunction-induced ferroptosis

It is shown that cells with OXPHOS deficiencies accumulate triacylglycerols enriched in polyunsaturated fatty acids (PUFAs), which are stored in lipid droplets, which reveal a novel protective mechanism against ferroptosis, which preserves membrane integrity against lipid peroxidation-driven ferroptosis.

G. Puertas-Frías, María José Saucedo-Rodríguez, Kristýna Čunátová et al. · 0 citations

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