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Tong-Mei Zhang

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Open access Sep 2026

The circulating tumor microenvironment in small-cell lung cancer: Vimentin-positive circulating tumor endothelial cells as drivers of metastasis and poor prognosis in a large cohort study.

Aggressive progression of small-cell lung cancer (SCLC) is orchestrated by a dynamic tumor microenvironment (TME). However, profiling this ecosystem remains a major constraint. The critical role of CD31+ aneuploid circulating tumor endothelial cells expressing vimentin (i.e. Vim+ CTECs amid Endo-MT process) in promotin...

Ying Wang, Fei Qi, Ming-Hang Zhang et al. · 0 citations

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