Open access
Sep 2026
TRIM47, stabilized by YTHDF3-mediated m6A modification, promotes cardiac lipid accumulation and aggravates diabetic cardiomyopathy
The results revealed that TRIM47 may contribute to the progression of DCM by promoting abnormal cardiac lipid metabolism, exacerbating inflammation and apoptosis, and these effects are partially mediated through the upstream m6A reader YTHDF3.
Wei-Yan Wang, Ling-Li Xie, Gui-Lan Chen et al.
· Molecular Metabolism · 0 citations