Author

Torsten Witte

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Open access Sep 2026

Impact of immunosuppressive therapy and clinical risk factors on the prevalence of low bone mineral density in rheumatic diseases

Background Osteoporosis is a severe comorbidity in inflammatory rheumatic diseases, impacting patient quality of life and healthcare costs. While general risk factors are known, the specific influence of various immunosuppressive therapies across different disease entities requires further characterization. This study...

Jan-Michael Brandt, Margret Patecki, Torsten Witte et al. · Frontiers in Medicine · 0 citations

Open access Sep 2026

Frequency of depression and anxiety in patients with inborn errors of immunity: a cross-sectional study

Inborn errors of immunity are chronic, genetically caused disorders that impair immune function and often increase susceptibility to infection. Many patients self-isolate because of infection-related concerns, which may increase the risk of mental health problems. This study evaluated symptoms of depression and anxiety...

Luca J. Wolff, Torsten Witte, Kai G. Kahl et al. · BMC Psychiatry · 0 citations

Review Open access Aug 2026

Expanding the clinical spectrum of CD3γ deficiency: comprehensive characterization of adult-onset disease and integrated reevaluation of all reported patients

Objective CD3γ deficiency is an ultrarare autosomal recessive inborn error of immunity characterized by immune dysregulation and variable immunodeficiency. To date, only 16 predominantly pediatric cases have been reported. Here, we describe two additional adult patients with CD3γ deficiency and provide a comprehensive...

Raphaela Obeng, A. Elsayed, Amos Takyi et al. · Frontiers in Immunology · 0 citations