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Author

Toshinari Takamura

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3 papers indexed here

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Open access Oct 2026

Diabetes attenuates weight reduction‐mediated liver fibrosis regression in persons with morbid obesity

ABSTRACT Aims Weight loss by laparoscopic sleeve gastrectomy (LSG) compared to medical weight loss (low‐calorie diet: LCD) ameliorates diabetes and metabolic dysfunction‐associated steatotic liver disease (MASLD). We aimed to evaluate changes in liver pathology 1‐year after LSG and their associations with metabolic fac...

Daiki Matsubara, Y. Takeshita, Masahiro Mori et al. · 0 citations
Open access Sep 2026

Distinct metabolomic signatures of SGLT2 inhibitor vs. sulfonylurea in a paired human liver biopsy study

This study aimed to elucidate how sodium-glucose cotransporter 2 (SGLT2) inhibitors and sulfonylureas differentially modulate hepatic metabolism in persons with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes (T2D). In this 48-week randomized, open-label, parallel-group trial, Japan...

Y. Takeshita, Hein Ko Oo, Yujiro Nakano et al. · 0 citations

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