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Tosiya Sato

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Open access Oct 2026

Power With Confounders in Clinical Trials Using External Controls.

When the number of patients is limited in clinical trials for rare diseases and pediatric developments, enrolling sufficient participants for confirmatory randomized clinical trials is difficult. Alternative trial designs using external controls have been proposed: augmented randomized clinical trials (ARCTs) and suppl...

Kentaro Kudo, Tosiya Sato · 0 citations

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