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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Trent M. Woodruff

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Open access Aug 2026

Molecular basis of diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptor C3aR

The complement anaphylatoxin receptor, C3aR, is a prototypical G protein-coupled receptor (GPCR) that plays multi-faceted roles in immune regulation, pro-inflammatory responses, neuroimmune modulation, and host defense mechanisms against pathogens. Recent structural coverage has provided important insights into C3aR ac...

Sudha Mishra, Manish K. Yadav, Annu Dalal et al. · 1 citation
Open access Jul 2026

Inherited C5aR2 deficiency leads to uncontrolled inflammatory T cell responses and autoinflammatory disease 2309676

A previously unrecognized CPM-dependent mechanism that balances C5aR1 and C5aR2 signaling to limit pathological T cell activation is uncovered, revealing an intrinsic complement-driven checkpoint that constrains effector T cell immunity.

Erin E. West, Nicolas S. Merle, Ayden Case et al. · 0 citations

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