Author

Troy Nations

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Open access Oct 2026

DNA2 nuclease inactivation induces DNA damage through a potential protein trapping mechanism.

DNA2 is a combined nuclease and helicase that processes long 5' flaps and other structures that occur during DNA replication and repair. Current models invoke an essential function of DNA2 in processing stalled replication forks to dampen toxic recombination based restart. As an essential replication stress response fa...

Katherine E. Baillie, Si-Jie Zhang, Jian Qin et al. · DNA Repair · 0 citations