Open access
Aug 2026
KLF4 in smooth muscle cell-derived progenitor cells is essential for angiotensin II-induced cardiac inflammation and fibrosis
The profibrotic differentiation trajectory of coronary artery-associated AdvSca1-SM cells in cardiac fibrosis is demonstrated, characterized by loss of stemness-related genes, including Klf4, but gain of expression of a profibrotic phenotype.
Si-Zhao Lu, Tysen Noble, J. Elkins et al.
· Arteriosclerosis, Thrombosis... · 0 citations