Colistin is a last-resort antibiotic used to treat infections caused by multidrug-resistant Gram-negative pathogens, including Klebsiella pneumoniae. Resistance to colistin can be explained by canonical mechanisms involving chromosomal mutations that activate lipid A modification pathways or by acquisition of plasmid-m...
Humberto Torres-Rodríguez, L. López-Jácome, C. Córdova-Fletes et al.· Journal of Global Antimicrob...· 0 citations
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a redoubtable global pathogen, distinguished from classical K. pneumoniae (cKp) by its ability to cause life-threatening, community-acquired infections in both healthy and immunocompetent individuals. While its pathogenicity is fundamentally anchored in...
Luis Duarte-Zambrano, J. Martínez-Barnetche, Alejandro Alvarado-Delgado et al.· Emerging Microbes and Infect...· 0 citations
Klebsiella aerogenes is an opportunistic pathogen increasingly associated with healthcare-associated infections and severe respiratory complications. However, it's in vivo adaptation during host colonization remains poorly understood. We characterized three clonal K. aerogenes ST93 isolates sequentially recovered on da...
Luis Duarte-Zambrano, Neli Nava-Domínguez, J. P. Ramírez-Hinojosa et al.· International Microbiology· 0 citations
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