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Author

U. GaykeA

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2 papers indexed here

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Open access Oct 2026

Development and In Vitro Evaluation of a pH-Responsive Hydrogel for Colon-Targeted Delivery of a Glucocorticoid

Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, requires effective local drug delivery to the colon while minimizing systemic corticosteroid exposure. Budesonide is a potent glucocorticoid with high local anti-inflammatory activity; however, its poor aqueous solubility and limited si...

U. GaykeA, Salunke Prajkta, Kotame R. NPatil S. D. Shinde V. S et al. · 0 citations
Open access Oct 2026

Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System (SMEDDS) of Atazanavir for Enhanced Solubility

The present study was aimed at the formulation and evaluation of a Self-Microemulsifying Drug Delivery System (SMEDDS) of Atazanavir to enhance its solubility and dissolution performance. Atazanavir is a poorly water-soluble antiretroviral drug, and its pH-dependent solubility can limit oral dissolution and absorption....

U. GaykeA, Bhagyashri Pawar, S. ShindeV et al. · 0 citations

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