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Author

U. Kleinekathoefer

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Open access Aug 2026

A self-assembled peptide forms α-helical nanopores for ultrasensitive biomarker profiling.

It is shown that the single peptide pPorA, derived from porin PorACj, self-assembles into flexible α-helical nanopores, inserts in lipid membranes and exists in distinct small- and large-conductance states, providing a versatile platform for ultrasensitive profiling of disease biomarkers.

Varsha Shaji, Rajeev Jain, Neethu Puthumadathil et al. · 0 citations

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