Open access
Sep 2026
Computational screening of 1-(2-methylphenyl) ethan-1-one derivatives for multi-target modulation of insulin signal transduction and glucose metabolism in diabetes mellitus
This is the first study to evaluate the predicted binding of substituted 1-(2-methylphenyl) ethan-1-one derivatives to PTP1B, DPP-4, α-glucosidase, and aldose reductase using an integrated computational workflow combining molecular docking, interaction profiling, and ADMET prediction.
P. Idakwoji, Udoeyop Favor, Okorie Claribel et al.
· Bioactive Molecules and Phar... · 0 citations