Author

Ugwu Okechukwu Paul-Chima

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Review Open access Aug 2026

From pathogen defence to precision health infrastructure: mRNA vaccines beyond infectious disease in preventive health, chronic disease management, and population wellbeing

Messenger RNA (mRNA) vaccine technology is often portrayed as a pandemic-era innovation for infectious disease control, but this perspective no longer reflects its expanding clinical and societal significance. Although global attention intensified during the SARS-CoV-2 pandemic, mRNA platforms are founded on more than...

Ugwu Okechukwu Paul-Chima, C. N. Ugwu, G. Anyanwu et al. · Frontiers in Bioengineering... · 0 citations

#explainable ai Review Sep 2026

Digital twins and explainable AI across the vaccine life cycle: from mRNA manufacturing to thermostability, cold-chain logistics, and immunisation services.

The evidence indicates that DTs are progressing from static simulations to operational twins for plasmid-to-mRNA production, supporting virtual commissioning, rapid scale-up and real-time optimisation, and XAI-enabled approaches improve stability prediction, and artificial intelligence of things (AIoT) architectures st...

Ugwu Okechukwu Paul-Chima, Michael Ben Okon, F. C. Ogenyi et al. · Vaccine · 0 citations