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Author

Ulrike Naumann

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Open access Aug 2026

The Hsd17b13P260S patient variant knock-in male mouse model provides translational insights into HSD17B13 biology

The Hsd17b13P260S mouse model is suggested to be translatable towards human physiology and useful for understanding the protective mechanisms of the human HSD17B13 P260S LoF variant, which protects against progression from MASLD to MASH and more severe types of liver disease.

C. Slabber, Felina Lenkeit, Kerri Grove et al. · 0 citations
Open access Aug 2026

Long-read target enrichment sequencing for rAAV integration site analysis in engineered clones with targeted viral insertion

Together, the engineered clonal controls and optimized LR-TES provide reference material and a technical framework supporting rAAV ISA in safety evaluation, particularly when high structural resolution and specificity are needed to interpret predominant integration events.

Erica Coratella, Myriam Lemmens, Mevion Oertli et al. · 0 citations

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