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Ulykbek Daurenov

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Review Open access Sep 2026

CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Chronic kidney disease is a major cardiovascular risk state in which conventional risk factors coexist with renal -specific mechanisms that promote vascular injury, myocardial remodeling, thrombosis, and arterial calcification. The cardiovascular burden becomes progressively greater as kidney function declines and is a...

Ulykbek Daurenov, Assiya Sherkhan, Sanzhar Mereyuly et al. · 0 citations
Open access Aug 2026

MODERN SURGICAL MANAGEMENT OF HIATAL HERNIA: CURRENT TECHNIQUES, INDICATIONS, AND CLINICAL OUTCOMES

Hiatal hernia is a common anatomical disorder characterized by displacement of the gastroesophageal junction and/or stomach through the esophageal hiatus of the diaphragm. Although many patients remain asymptomatic, clinically significant hiatal hernias ma y cause gastroesophageal reflux disease, dysphagia, regurgitati...

Ulykbek Daurenov, Olzhas Nurbay, Diana Baszhan et al. · 0 citations
Open access Aug 2026

THE ROLE OF THE GUT MICROBIOME IN THE DEVELOPMENT AND PROGRESSION OF GASTROINTESTINAL DISEASES: CURRENT EVIDENCE AND FUTURE PERSPECTIVES

The gut microbiome is a complex ecosystem consisting of bacteria, archaea, fungi, viruses, and other microorganisms that interact continuously with the intestinal epithelium, immune system, and metabolic pathways of the host. Increasing evidence demonstrates that alterations in the composition and function of the gut m...

Ulykbek Daurenov, Dana Suyunbay, Alua Toqseiıt et al. · 0 citations
Open access Aug 2026

КАРДИОМЕТАБОЛИЧЕСКИЙ РИСК: СОВРЕМЕННЫЕ ПОДХОДЫ К ДИАГНОСТИКЕ, ПРОФИЛАКТИКЕ И ЛЕЧЕНИЮ

Кардиометаболический риск представляет собой комплекс взаимосвязанных метаболических и сосудистых факторов, определяющих вероятность развития сердечно -сосудистых заболеваний, сахарного диабета 2 типа, хронической болезни почек и сердечной недостаточности. В последние годы концепция оценки кардиометаболического риска п...

Ulykbek Daurenov, Дильбар Аршидинова, Галымжан Коразов et al. · 0 citations
Open access Jul 2026

CARDIORENAL SYNDROME: CURRENT CONCEPTS, DIAGNOSTIC CHALLENGES AND MANAGEMENT

This work states that despite substantial advances in diagnostic techniques and therapeutic strategies, CRS remains associated with high morbidity, mortality, prolonged hospitalization, and increased healthcare costs.

Ulykbek Daurenov, Nurtileu Saifulla, Balausa Rakhmatulla et al. · 0 citations
Review Open access Jul 2026

BIOLOGIC THERAPY IN MODERATE-TO-SEVERE PSORIASIS: CURRENT EVIDENCE AND EMERGING TRENDS

The current evidence regarding biologic therapy for moderate-to-severe psoriasis is summarized, highlighting mechanisms of action, clinical efficacy, safety, emerging biologic agents, and future perspectives in personalized dermatologic care.

Perizat Dauletbayeva, Ulykbek Daurenov, Diyana Bekzatova · 0 citations
Review Open access Jul 2026

ARTIFICIAL INTELLIGENCE IN ENDOCRINOLOGY: EMERGING APPLICATIONS IN DIABETES AND OBESITY MANAGEMENT

Current evidence regarding the emerging applications of AI in diabetes and obesity management is summarized, recent technological advances are discussed, implementation barriers are highlighted, and future directions for AI-assisted endocrine care are explored.

M. Abdumalikova, Ulykbek Daurenov, Dana Suyunbay et al. · 0 citations
Open access Aug 2026

MECHANISMS OF TUMOR IMMUNE EV ASION AND STRATEGIES TO ENHANCE ANTITUMOR IMMUNITY

Current approaches increasingly focus on combination strategies designed to simul taneously restore antigen presentation, improve immune -cell trafficking, overcome immunosuppression, reverse T -cell dysfunction, and increase tumor immunogenicity.

Ulykbek Daurenov, Ayaulym Sartaubai, Assiya Sherkhan et al. · 0 citations
Review Jul 2026

CURRENT ADVANCES IN CLINICAL ONCOLOGY: CHALLENGES AND FUTURE PERSPECTIVES

The continued integration of genomics, AI-driven diagnostics, biomarker-guided therapies, and multidisciplinary clinical approaches is anticipated to improve patient outcomes while promoting precision oncology as the new standard of cancer care.

Ulykbek Daurenov, Dastan Turdykul, Dana Suyunbay et al. · 0 citations
Review Open access Jul 2026

NOVEL DIRECTIONS IN LIPID-LOWERING THERAPY FOR THE PREVENTION OF CARDIOVASCULAR DISEASES

Current evidence regarding novel lipid-lowering therapies, their mechanisms of action, clinical efficacy, safety profiles, and future perspectives in the prevention of cardiovascular diseases are summarized.

Galymzhan Qorazov, Ulykbek Daurenov, Aisulu Amirbai et al. · 0 citations

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