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Chitosan-stabilized Ag–Ni bimetallic nanoparticles for quantitative antibacterial evaluation and prospective wound-coating applications
Bimetallic silver–nickel nanoparticles (Ag–Ni BMNPs) stabilized with chitosan were synthesized and systematically characterized to evaluate their antibacterial properties and potential for proof-of-concept wound-coating applications. The synthesized nanoparticles were characterized using UV–Vis spectroscopy, Fourie...
Computational Discovery of Novel CYP51 Inhibitors for Antifungal Therapy Against Aspergillus fumigatus.
Findings identify Boeravinone D, Nimbidin, and 7-acetyl neotrichilenone as promising CYP51 inhibitors and all three candidates showed favorable ADMET profiles, although 7-acetyl neotrichilenone may require optimization to improve solubility.