Ursula Storch

From plasma membrane to lysosomes: expanding roles of TMEM63/OSCA channels in mechanosensation and intracellular signaling

Mechanosensation enables cells to detect physical forces, including membrane stretch, pressure, shear stress, and osmotic stress, and to convert them into biochemical and electrical signals that regulate cellular function. Among the emerging families of mechanosensitive proteins, TMEM63/OSCA channels have recently been...