Author

Urszula N. Wasko

h-index 4 View on Semantic Scholar

We have 3 of 22 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Abstract B073: Rational combination strategies enhance the depth and durability of zoldonrasib antitumor response in preclinical models of KRAS G12D pancreatic cancer

R Rational combination strategies of zoldonrasib with mechanistically distinct agents can enhance antitumor activity relative to the respective monotherapies, and potentially delay emergence of resistance to RAS(ON) inhibition in preclinical models of KRAS G12D PDAC.

Urszula N. Wasko, Yong-Xian Zhuang, Marie Ménard et al. · Cancer Research · 0 citations

Sep 2026

Abstract B008: Pan-RAS-GTP inhibition disrupts the KRAS-SHH axis to reprogram cancer-associated fibroblast subtypes and reduce stiffness in pancreatic cancer

Oncogenic KRAS mutations are present in ∼95% of pancreatic ductal adenocarcinoma (PDAC) cases and have long been considered undruggable. The recent clinical emergence of RAS inhibitors marks a transformative moment in PDAC therapy, yet their impact on the tumor microenvironment (TME) remains largely unknown. This is...

Marie C. Hasselluhn, Allison C. Hess, L. Tomassoni et al. · Cancer Research · 0 citations

Open access Aug 2026

Developmental and MAPK-responsive transcription factors regulate distinct malignant cell states and associated genetic dependencies in pancreatic cancer

The authors apply ARACNe and metaVIPER to published scRNA-seq datasets to characterize pancreatic cancer subtypes, identifying six distinct cell states as well as their mechanistic determinants.

P. Laise, Mikko M. Turunen, Álvaro Curiel-García et al. · Nature Genetics · 1 citation