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Author

V. A. Yakovlev

2 papers indexed here

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Open access Oct 2026

A two-component mRNA vaccine combining B-cell and T-cell immunogens of SARS-CoV-2 induces humoral and cellular immune responses in mice

INTRODUCTION. Despite the effectiveness of existing COVID-19 vaccines, the emergence of new SARS-CoV-2 variants necessitates the development of immunogens capable of eliciting a broad, cross-reactive immune response. A promising approach is the development of mRNA vaccines that induce both humoral and T-cell respons...

M. B. Borgoyakova, A. P. Rudometov, S. V. Sharabrin et al. · 0 citations
Open access Oct 2026

Administration of the mRNA-H5 vaccine to ferrets via jet injection provides protective immunity against the H5N1 influenza virus

INTRODUCTION. The highly pathogenic avian influenza virus subtype H5Nx is rapidly evolving and infecting various species of wild and domestic mammals, including cattle, highlighting its pandemic potential for humans. To combat the pandemic threat, it is essential to develop suitable vaccine platforms, including mRNA...

V. R. Litvinova, A. Gudymo, V. A. Yakovlev et al. · 0 citations

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