Vanillin-Derived Multifunctional Agents: Structure-Based Design, Docking, and In Vitro Evaluation of Antitubercular, Anti-Inflammatory, and Antioxidant Activities
Tuberculosis remains a major global health burden, highlighting the urgent need for new therapeutic agents with improved efficacy and safety. In this study, a series of vanillin-derived biphenyl ether analogues inspired by the nimesulide scaffold was designed and synthesized as multifunctional candidates targeting tube...