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V. Cowling

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Open access Sep 2026

Not all TOP RNAs are created equal: 3’UTR length and TSS selection predict the translational regulation of LARP1-bound mRNAs in CD4+ T cells

Naïve T cells are poised for activation and contain a pool of translationally repressed ribosomal protein (RP) mRNA prepared to induce ribosome biogenesis to support protein synthesis, cell growth and proliferation. RP mRNA are the prototypical members of a class of transcripts initiating at cytosine followed by a CU r...

Alison Galloway, V. Cowling · 0 citations

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