Introduction. COVID-19, caused by SARS-CoV-2, remains a significant global health issue. Since late 2021, the Omicron variant has become dominant, characterized by high transmissibility but reduced virulence. Studying the regional characteristics of the epidemic process during its circulation is essential for assessing...
A. Gladkikh, Alena Khalilova, M. Popova et al.· Journal of microbiology, epi...· 0 citations
The escalating antimicrobial resistance in
Klebsiella pneumoniae
underscores the urgent need for alternative therapies. Phage therapy represents a promising approach owing to its specificity, phage self-replication, and potential synergy with antibiotics. Yet, the narrow host range of phages and rapid emergence...
Sofia Platova, R. Gorodnichev, A. Shabalina et al.· Frontiers in Microbiology· 0 citations
Current high-throughput sequencing platforms enable routine whole-genome sequencing of bacteria via clonal amplification from primary samples, followed by DNA extraction, library preparation, and sequencing. This approach enriches bacterial DNA while removing contaminating nucleic acids, allowing efficient genomic sequ...
Mikhail Bezruchko, O. Freylikhman, E. Khalilov et al.· PLoS Neglected Tropical Dise...· 0 citations
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