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Author

V. Dobričić

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2 papers indexed here

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Open access Oct 2026

Oxaprozin-Based Amide Derivatives as Multifunctional Agents: Synthesis, Characterization, and Comprehensive Biological Profiling

Background/Objectives: Inflammation plays a role at multiple levels, contributing to tumorigenesis, cellular proliferation, cell survival, and metastasis. The established link between chronic inflammation and tumor development has shifted the therapeutic focus toward nonsteroidal anti-inflammatory drugs, which exert th...

Anđela Gogić, Miloš Nikolić, Nikola V. Nedeljković et al. · 0 citations
Aug 2026

Design of fluorinated triazinoindoles as highly potent and markedly selective ALR2 inhibitors: synthesis, in silico and in vitro evaluation of promising lead compounds.

Aldose reductase (ALR2) is widely recognized as a therapeutic target for diabetic complications and is involved in the metabolism of reactive aldehydes generated during hyperglycemia and lipid peroxidation. To investigate the effect of fluorination on inhibitory potency and enzyme selectivity, we designed and synthesiz...

L. Kováčiková, Terezia Teplanova, M. Májeková et al. · 0 citations

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