FROM PLANT DEFENSE TO HUMAN THERAPEUTICS: MULTI-TARGET CHEMISTRY AND AI-GUIDED DISCOVERY OF RESISTANCE-RETARDING ANTIBACTERIALS
Antimicrobial resistance (AMR) is a major threat to modern medicine, driven largely by the widespread use of single-target antibiotics that create strong, narrow selective pressures and can be overcome by a single genetic change in the pathogen. This conceptual review argues that plants, which have been combating bacte...