Peptidomics-guided 3D structural-mechanistic investigation of bovine colostrum peptides reveals multi-targeted in silico and in vitro antidiabetic and antioxidant potential
Multi-target inhibition of α-amylase, α-glucosidase, and human aldose reductase can significantly address postprandial hyperglycemia and subsequent diabetic complications, yet bovine colostrum peptides remain largely unscreened against these enzymes. Using a peptidomics-guided, integrated in silico and in vitro approac...