Author

V. Hungria

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Open access Sep 2026

Daratumumab Plus Bortezomib, Lenalidomide, and Dexamethasone in Newly Diagnosed Multiple Myeloma: Transplant-Ineligible Subgroup Analysis of CEPHEUS.

The phase III CEPHEUS trial (ClinicalTrials.gov identifier: NCT03652064) of patients with transplant-ineligible (TIE) or transplant-deferred newly diagnosed multiple myeloma (NDMM; N = 395) demonstrated improved overall minimal residual disease (MRD) negativity rates among patients achieving ≥complete response and prog...

S. Usmani, T. Facon, V. Hungria et al. · Journal of Clinical Oncology · 0 citations

Review Open access Oct 2026

Dysregulation of the Bone Marrow Immune Microenvironment and Clinical Outcomes in Multiple Myeloma

Multiple myeloma (MM) is characterized not only by malignant plasma cell proliferation but also by progressive dysregulation of the bone marrow immune microenvironment (BMIME). Increasing evidence suggests that disease progression, therapeutic resistance, and clinical outcomes are associated with dynamic interactions b...

Maria P. Ghirardi, Patrícia Brandalise, M. Berraondo et al. · Immuno · 0 citations