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V. Iskra

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Open access Aug 2026

RNA-dependent association of the pyruvate dehydrogenase complex with mtDNA-containing assemblies supports mitochondrial translation

It is shown that the pyruvate dehydrogenase complex (PDHc), which supplies acetyl-CoA to the tricarboxylic acid cycle, is a component of this machinery in Saccharomyces cerevisiae and acts as a non-catalytic component of the RNA-dependent architecture that supports mitochondrial gene expression.

Johannes Hagen, Nupur Sharma, Felix Thoma et al. · 0 citations

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