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Author

V. Jaitak

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Review Aug 2026

Pyrimidine-containing Heterocyclic Anticancer Agents: Systematic Development, SAR, and Mechanistic Pathways.

Pyrimidine-containing hybrids emerge as a privileged scaffold in medicinal chemistry for the development of effective, multitargeted anticancer agents with improved pharmacological profiles and reduced off-target effects.

Bhim Singh, Ankita Devi, V. Jaitak · 0 citations
Aug 2026

Structure-based elucidation of thiazine inhibitors targeting estrogen receptors alpha: pharmacophore modeling, virtual screening, molecular docking, MD, and DFT approach.

This research developed a promising lead molecule (HIT1) as a therapeutic approach for ER-positive breast cancer through pharmacophore model-based drug design of thiazine derivative targeting ERα via pharmacophore model-based drug design.

M. Sanjeev, Bhim Singh, Kailash Jangid et al. · 0 citations

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