Author

V. Maisons

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Review Open access Sep 2026

Intensification of blood pressure lowering therapeutics based on diuretics versus usual management for uncontrolled hypertension in patients with moderate to severe chronic kidney disease (THINK): protocol for an open label, two-parallel group, cluster randomised controlled, superiority, phase 3 tri

Abstract Introduction Hypertension is the primary modifiable risk factor for cardiorenal complications of chronic kidney disease (CKD). It is well established that lowering blood pressure (BP) in patients with CKD reduces renal and cardiovascular complications. The guidelines advise starting the BP-lowering drug with A...

F. Le Vilain-Abraham, J. Halimi, P. Rossignol et al. · BMJ Open · 0 citations

Open access Sep 2026

Impact of renin–angiotensin system inhibitors discontinuation in advanced chronic kidney disease: a target trial emulation

ABSTRACT Background Renin–angiotensin system (RAS) inhibitors are a cornerstone of cardiovascular and kidney risk modification in chronic kidney disease (CKD). Yet, they are often discontinued in advanced CKD to limit adverse effects or to delay kidney replacement therapy (KRT). Methods From the CKD-Renal Epidemiology...

V. Maisons, M. Costes-Albrespic, Sophie Liabeuf et al. · Clinical Kidney Journal · 0 citations