Background: Recombinant (RIV) and cell culture-based inactivated (ccIIV) influenza vaccines could improve seasonal influenza prevention; however, evidence is limited in how protection may differ among non-egg-based vaccines. Methods: We conducted a randomized trial of RIV versus ccIIV to compare vaccine immunogenicity...
Kelsey M. Sumner, Emma K. Noble, Lauren Grant et al.· medRxiv· 0 citations
Background/Objectives: Humans are primarily infected by two distinct seasonal influenza A virus (IAV) subtypes, A(H1N1)pdm09 and A(H3N2). Because IAV mutates rapidly, it continuously escapes existing protective antibodies. However, repeated exposure to these evolving strains increases the diversity of virus-specific me...
M. Mishina, C. Horn, Zachary Ende et al.· Vaccines· 0 citations
During the high severity season of 2024–25, CDC with public health partners sequenced and analyzed genomes of >10,000 influenza viruses for antiviral resistance markers and provided information on susceptibility profile to all approved antiviral medications and on replicative fitness of representative drug-resistant vi...
Mira C. Patel, Ha T. Nguyen, Philippe Noriel Q. Pascua et al.· Microbiology spectrum· 1 citation
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