Lipid Dysregulation and Impaired Resolution of Inflammation in Genetic Forms of Parkinson’s Disease: Potential Links and Knowledge Gaps
Dysregulation of lipid metabolism plays an important role in the development of Parkinson’s disease (PD), particularly in PD monogenic forms. At the same time, accumulating evidence points to impaired resolution of neuroinflammation mediated by specialized pro-resolving mediators (SPMs), although mutation-specific data...