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Open access Aug 2026

Estimating the Relative Vaccine Efficacy of mRNA-1010 to High-Dose Influenza Vaccine in Adults ≥65 Years Using a Correlate of Protection Framework

Background/objective: Older adults experience a disproportionate burden of severe influenza. In the P303 trial (NCT058279789), mRNA-1010 showed greater immunogenicity versus high-dose inactivated influenza vaccine (HD-IIV4) in adults ≥65 years of age. Here, we used a correlate-of-protection framework to estimate the re...

V. Nguyen, Ethan Settembre, John Youhanna et al. · 0 citations

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